Yoav Gilad, PhD

The Gilad lab focuses on studying genetic and regulatory differences between humans and our close evolutionary relatives. Our long term goal is to identify the genetic basis of human-specific traits, including genetic variation that underlies higher susceptibility to certain diseases and disorders in humans than in other primates.

Weizmann Institute of Science
Rehovot, Israel
Ph.D. - Molecular Genetics
2003

Weizamnn Institute of Science
Rehovot, Israel
M.Sc. - Molecular Genetics
2000

Ben Gurion University
Beer-Sheva, Israel
B.Sc. - Molecular Genetics and Biochemistry
1998

Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids.
Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids. bioRxiv. 2024 Sep 03.
PMID: 39282424

Cell-type and dynamic state govern genetic regulation of gene expression in heterogeneous differentiating cultures.
Cell-type and dynamic state govern genetic regulation of gene expression in heterogeneous differentiating cultures. bioRxiv. 2024 May 03.
PMID: 38746382

Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons.
Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons. Cell Genom. 2024 Mar 13; 4(3):100509.
PMID: 38430910

Guided Differentiation of Pluripotent Stem Cells for Cardiac Cell Diversity.
Guided Differentiation of Pluripotent Stem Cells for Cardiac Cell Diversity. bioRxiv. 2024 Feb 12.
PMID: 37502898

Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons.
Genetic regulatory effects in response to a high cholesterol, high fat diet in baboons. bioRxiv. 2023 Nov 20.
PMID: 37577666

Guided Differentiation of Pluripotent Stem Cells for Cardiac Cell Diversity.
Guided Differentiation of Pluripotent Stem Cells for Cardiac Cell Diversity. bioRxiv. 2023 Nov 17.
PMID: 37502898

Induced Pluripotent Stem Cells in Disease Biology and the Evidence for Their In Vitro Utility.
Induced Pluripotent Stem Cells in Disease Biology and the Evidence for Their In Vitro Utility. Annu Rev Genet. 2023 11 27; 57:341-360.
PMID: 37708421

The relationship between regulatory changes in cis and trans and the evolution of gene expression in humans and chimpanzees.
The relationship between regulatory changes in cis and trans and the evolution of gene expression in humans and chimpanzees. Genome Biol. 2023 09 11; 24(1):207.
PMID: 37697401

Evolutionary insights into primate skeletal gene regulation using a comparative cell culture model.
Evolutionary insights into primate skeletal gene regulation using a comparative cell culture model. PLoS Genet. 2022 03; 18(3):e1010073.
PMID: 35263340

Human embryoid bodies as a novel system for genomic studies of functionally diverse cell types.
Human embryoid bodies as a novel system for genomic studies of functionally diverse cell types. Elife. 2022 02 10; 11.
PMID: 35142607

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